Charcot foot can drastically alter the structure and function of the foot, leading to significant changes in biomechanics. The loss of normal arch support and the development of deformities, such as a flattened midfoot or a protruding bone, can shift weight-bearing areas to abnormal points. This increases the risk of pressure ulcers, further infections, and difficulty with mobility. Left untreated, these changes can result in severe complications, including amputation.